Prelox® is a proprietary blend of L-Arginine and Pycnogenol®. Together they increase nitric oxide production, stimulate circulation and blood flow and protect blood vessels from the damage that can occur from normal aging. This combination helps to improve blood flow into the vessel and enhances the vessels responsiveness to that flow. And that helps to achieve and sustain better erections.
The key to unlock a constricted artery is a mediator called nitric oxide. Nitric oxide is generated from L-arginine and supplementation with this amino acid is known to ease dilatation of arteries, enabling them to carry more blood volume. Pycnogenol® works by accelerating the cellular machinery involved in converting L-arginine into nitric oxide. Prelox® delivers abundant L-arginine as starting material in combination with Pycnogenol® for accelerated processing of the amino acid into nitric oxide. This synergistic principal provides the basis for the ability of previously mal-responsive arteries to then deliver blood volume sufficient for a healthyer erection.
In Prelox® the key component Pycnogenol® accelerates production of nitric oxide while the second componentL-arginine ensures sufficient supply of the starting material. The synergistic activity of both components in Prelox® is patented.
A first clinical investigation of 40 men with compromised erections showed that taking L-arginine alone for one month did have an effect, though only in five percent of the men. The following month all men took Pycnogenol® in addition to L-arginine (Prelox® blend) and now 80% of the men experienced restored erectile function.
In a clinical study carried out by Steven Lamm M.D. in New York, 81% of men supplemented with Prelox® for 6 weeks showed an improved erectile function. 78% of the men judged Prelox® to be effective.
A study in which all participants are unknowingly at one time receiving active treatment and at another time an inactive placebo and then cross-over following a discontinuation period, is regarded the gold standard in clinical research. Fifty men presenting moderate erectile problems related to unhealthy life-styles (overweight, mild hypertension) were investigated with Prelox® or placebo in such cross-over fashion. Men were assigned to either group A or B. During the first month group B got Prelox®, while A received look-alike dummy tablets. Then both groups discontinued tablets for one month (washout period) and then switched to the opposite regimen [Stanislavov et al., 2008].
While a group of men was taking Prelox® for a month the erectile quality significantly increased, and when they discontinued the regimen for a month this effect largely faded. The study demonstrated increased stamina and sexual pleasure in men in response to Prelox®. Men reported to lead researcher Romil Stanislavov MD that it was easier for them to initiate and sustain an erection.
A study spanning an investigational period over half a year was carried out with 110 men with moderately impaired erectile function.
This study demonstrates that no habituation effects occur with Prelox® and the benefits do not fade, but rather further improve during long-term supplementation for six months.
After this period, erectile function was even better than it already was after three months. This study identified improved sexual desire in response to Prelox® as well as greater sexual and orgasmic satisfaction.